KMID : 0191120220370330254
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Journal of Korean Medical Science 2022 Volume.37 No. 33 p.254 ~ p.254
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Risk of Subsequent Events in Patients With Minor Ischemic Stroke or High-Risk Transient Ischemic Attack
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Lee Keon-Joo
Shin Dong-Woo Park Hong-Kyun Kim Beom-Joon Park Jong-Moo Kang Kyu-Sik Park Tai-Hwan Lee Kyung-Bok Hong Keun-Sik Cho Yong-Jin Kim Dong-Eog Ryu Wi-Sun Lee Byung-Chul Yu Kyung-Ho Oh Mi-Sun Lee Soo-Joo Kim Jae-Guk Lee Jun Cha Jae-Kwan Kim Dae-Hyun Kim Joon-Tae Choi Kang-Ho Choi Jay-Chol Lesen Eva Hedberg Jonatan Tank Amarjeet Fita Edmond G. Song Ji-Eun Lee Ji-Sung Lee June-Young Bae Hee-Joon
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Abstract
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This study aimed to present the prognosis after minor acute ischemic stroke (AIS) or transient ischemic attack (TIA), using a definition of subsequent stroke in accordance with recent clinical trials. In total, 9,506 patients with minor AIS (National Institutes of Health Stroke Scale ¡Â 5) or high-risk TIA (acute lesions or ¡Ã 50% cerebral artery steno-occlusion) admitted between November 2010 and October 2013 were included. The primary outcome was the composite of stroke (progression of initial event or a subsequent event) and all-cause mortality. The cumulative incidence of stroke or death was 11.2% at 1 month, 13.3% at 3 months and 16.7% at 1 year. Incidence rate of stroke or death in the first month was 12.5 per 100 person-months: highest in patients with large artery atherosclerosis (17.0). The risk of subsequent events shortly after a minor AIS or high-risk TIA was substantial, particularly in patients with large artery atherosclerosis.
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KEYWORD
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Minor Ischemic Stroke, Ischemic Attack, Transient, Event Outcome, Stroke Recurrence
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